The medication Actos, as it is the case for other thiazolidinediones, can contribute to a person retaining fluids when used on its own or in grouping with other antidiabetic materials, such as insulin. It is possible for fluid retention to result in or worsen heart failure. It is a good idea for patients to be thoroughly examined for any heart failure signs and indications. It has been advised that Actos no longer be used if a patient develops any deterioration in cardiac status. Actos is not suggested for use in patients with New York Heart Association (NYHA) Class III and IV cardiac status, since these patients were not examined throughout clinical trials.
In one 16-week U.S. double-blind, placebo-controlled clinical trial that involved 566 type 2 diabetes patients, Actos was administered in doses of 15 mg and 30 mg grouped with insulin. These patients were evaluated in comparison to insulin therapy by itself. The trial included patients suffering from long-term diabetes and an increased frequency of pre-existing medical conditions that included: arterial hypertension (57.2%), peripheral neuropathy (22.6%), coronary heart disease (19.6%), retinopathy (13.1%), myocardial ischemic attack (4.1%), and congestive heart failure (2.3%).
Actos may also be associated with causing symptoms of congestive heart failure, rapid weight gain, shortness of breath, edema, and fluid retention. It is possible for Actos to make symptoms worse in individuals who already have a history of heart problems or heart failures, in which the drug could cause congestive heart failure. The potential dangers include low blood sugar or hyperglycemia when taking Actos along with insulin, metformin, sulfonlurea, or other diabetes pharmaceuticals. It is not recommended that individuals with active liver disease, edema, history of heart failure, or type 1 diabetes take Actos.
As a drug that’s been on the market since 1999, Actos has been consumed by many patients suffering from type 2 diabetes. At Reiff and Bily, our Actos side effect attorneys in Philadelphia are concerned about the serious complications that the drug can cause patients to suffer. Although our firm is not currently pursuing lawsuits on this drug, we are at present investigating labeling history and drug warnings for Actos. For more information, please call us today at (800) 421-9595.